Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones
نویسندگان
چکیده
منابع مشابه
Route of administration induced in vivo effects and toxicity responses of Zinc Oxide nanorods at molecular and genetic levels
Zinc oxide (ZnO) nanoparticles have received growing attention for several biomedical applications. Nanoparticles proposed for these applications possess the potential to interact with biological components such as the blood, cells/ tissues following their administration into the body. Hence we carried out in vivo investigations in Swiss Albino Mice to understand the interaction of ZnO nanorods...
متن کاملRoute of administration induced in vivo effects and toxicity responses of Zinc Oxide nanorods at molecular and genetic levels
Zinc oxide (ZnO) nanoparticles have received growing attention for several biomedical applications. Nanoparticles proposed for these applications possess the potential to interact with biological components such as the blood, cells/ tissues following their administration into the body. Hence we carried out in vivo investigations in Swiss Albino Mice to understand the interaction of ZnO nanorods...
متن کاملsynthesis and characterization of some new cyclometalated organoplatinum(ii) complexes containing phosphite ligand
در این تحقیق روشی جهت سنتز یک سری از کمپلکس های پلاتین (ii) حاوی لیگاند های دهنده ی فسفری شامل فسفیت و فسفین ارائه شده است. واکنش پیش ماده ی پلاتین (ii)،trans/cis- [ptcl2(sme2)2] ، با 2 اکی مولار از لیگاند p(oph)3در حلال بنزن کمپلکس1، cis-[ptcl2(p(oph)3)2] را تولید می نماید. جهت سنتز کمپلکس سایکلو متال فسفیتی، کمپلکس 1 با 1 اکی والان واکنشگر ptcl2 در حلال زایلن در شرایط رفلاکس زیر گاز آرگون م...
Some chemistry of tris(pyrazolyl)methylthiolate derivatives.
An efficient synthetic method for the preparation of TAS tris(pyrazolyl)methylthiolate (3) is reported. Nucleophilic exchange reactions with 3 gave (pyr)C(=S)SC(pyr)3 (4) and MeSC(pyr)3 (5). 5 acts as scorpionate ligand in [MeSC(pyr)3Cr(CO)3] (6), from the decomposition of TDAE2+ [SC(pyr)3Mo(CO)3-]2 by SO2FCl TDAE2+[O=MoF4-F-Mo(=O)Cl4]2- (8) was isolated. The X-ray structures of 3-6 and 8 are d...
متن کاملThe design of anti-inflammatory drugs: some considerations based on pessimism, molecular pharmacology and cellular pathology.
Professor Ariens in another context1 (and elsewhere in this Symposium) has drawn attention to the possibilities of molecular pharmacology serving as a guide to the development of new drugs. In pursuit of this theme, I should like to examine with you later in this lecture some of the biological and molecular characteristics of the principal non-steroid anti-inflammatory drugs known to us today, ...
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ژورنال
عنوان ژورنال: Journal of Enzyme Inhibition and Medicinal Chemistry
سال: 2021
ISSN: 1475-6366,1475-6374
DOI: 10.1080/14756366.2021.1887169